CMB 311 Lecture Notes - Lecture 3: Carboxylic Acid, Amine, Leucine

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Transport materials into and out of the cell. Vary greatly in molecule weight, shape, and conformational dynamics. Definition: an amino acid is a carboxylic acid with an amino group attached to the a-carbon. Remember the common nomenclature for carboxylic acids, in which the first carbon after the cooh (carboxyl) group is the a-carbon. In iupac nomenclature, the carbon in cooh is number 1, and the next carbon (the a-carbon) is number 2. In the common nomenclature, subsequent carbons are designated greek letters; Remember, the a-amino group refers to its position relative to the carboxyl group. Biology uses exclusively the l stereoisomer for protein synthesis. The r group determines the amino acid a-carbon is asymmetric. There are 20 different amino acids found in proteins. (*must know*) These are distinguished by the structures of their r groups. Each amino acid is given a three-letter abbreviation and a one-letter abbreviation. Both of these sets of abbreviations are important to know.

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