BIOL 243L Lecture Notes - Lecture 2: Kinetochore, Protein Structure, Cleavage Furrow
Document Summary
The process of a cell dividing into 2 identical daughter cells. Occurs when cells reach a certain age. Means of body growth, replacing older cells, and repairing injured parts of the body. Cells spend most of their time in interphase. G1: cells grow larger; duplication of organelles. S: dna is duplicated exactly and the amount of dna doulbes. G2: more growth, enzymes and other proteins are synthesized and cell prepares for mitosis. Mitosis=the division of the nucleus to produce 2 diploid nuclei: occurs at end of interphase. Chromosomes (comprised of 2 sister chromatids) condense. Chromosomes line up at equator at the metaphase plate. Microtubules that make up spindle fibers extend from the poles to center of the cell. Chromosomes move randomly until they attach at their kinetochores to polar fibers from both sides of the centromeres. Kinetochores= protein structure where spindle fibers attach to pull sister chromatids apart. The pair centromeres begin to move apart.