NEU 365W Lecture Notes - Lecture 9: Insecticide, Ephedrine, Cocaine Dependence

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25 May 2020
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Describe psychostimulants historically, and how-why they became classified as addictive . Describe effects/ side-effects of acute and repeated psychostimulant administration. Appraise the links between psychostimulant mechanism action, physiology, & behavior. Describe the rationale behind the dose-dependent effects of psychostimulants; depict this effect (i. e. in graph-form) Estimate addiction potential of drugs based on route of administration & pharmacokinetics (this pertains to psychostimulants, but is generalizable across drugs) Describe brain circuits, neurotransmitters, and hormones involved in the development of psychostimulant addiction, negative affective states, and relapse. Describe the physiological symptoms of drugs (psychostimulants, opiates, alcohol) when they are on board or someone is withdrawing from their repeated use. Identify what druga person is on/off based on their physiological symptoms. Part of sympathetic nervous system (autonomic nervous system) - fight-or-flight response. Drugs don"t have an effect of their own - only mimic what is already there. Psychostimulants = sympathomimetics - mimetics of sympathin .

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