NEU 365W Lecture Notes - Lecture 16: Fractional Anisotropy, Longitudinal Study, Magnetic Resonance Imaging
Document Summary
04/16 lecture 16 notes: comorbid alcohol use/disorders & mental illness: neural trajectories & Comorbid mental illness biological factor that contributes to addiction: percentage of prevalence of drug disorders, general population ~10, drug disorders much larger! of any psychiatric illness. Mani (bipolar disorders) ~35% - one of the highest rates of addiction out. Onset of drug use and addiction during this period. Bipolar disorder: disease heterogeneity in bipolar disorder, alcohol & suicide attempts. Longitudinal work: neural predictors, trajectories, associated outcomes: preliminary studies. Brain development during adolescence: dynamic brain changes (especially frontal cortex & frontolimbic connections) Connections continue between the cortex and limbic system continue to be made. Increase in myelination: healthy development, more mature and adaptive behavioral responses (increase in efficiency) Control of impulses and risky behaviors: altered development. Brain circuitry regulating emotions and impulses: amygdala (emotions, striatum (impulses & reward processing, pfc (emotional regulation and impulse control)
