BIO-183 Lecture Notes - Lecture 11: Neutrophil, Vomiting, Phagocytosis
Document Summary
Very old and very young weakened immune system: genetic: congenital immunodeficiency, aids- acquired, surgery and organ transplants, underlying disease: cancer, liver malfunction, diabetes. True pathogen: capable of causing disease in healthy people with normal immune systems: mrsa, malaria. Opportunistic pathogen: disease when the host"s defenses are compromised or when they become established in a part of the body unnatural to them. Virulence- ability of a microbe to establish itself in a host and cause damage. Staph aureus: enter vis nicks, abrasions in skin. Infectious dose: minimum number of microorganisms needed to cause infection. Adhesion: docks and attaches to the host cell- needed for disease to progress. Phagocytes: immune cells that will gobble up pathogens. Kinase: exotoxin: some microorganisms release toxins: botulism. Neurotoxins, hemotoxins: hemolysins- destroy rbc, fever: enzymes: toxins, induce excessive hot defense response. Some organisms cause damage to host by causing excessive immune response: pneumonia: inflammation of lungs. Chronic: persists for a long period of time.
