BIO-183 Lecture Notes - Lecture 12: Human Microbiota, Lysozyme, Epidermis
Document Summary
Immune cells- born in bone marrow, mature in the thymus, then go to the lymph nodes. Hematopoiesis: production of blood cells *in the bone marrow. Chemotasis: how cells attracted by the chemical stimuli to site of need. Fever: 2nd line- turn up heat to drive out intruder : pyrogen, exogenous: released by infectious agents (microorganisms, endogenous- released by immune cells to initiate the fevers. Fever= fighting off infection, but too much can impact homeostasis. Interferon fights viruses: iv- natural antiviral produced by the body. Complement- proteins produced in the liver that can trigger the destruction/lysis of pathogens: proteins bind to pathogen, pores form, lysis of the bad cell . Monocytes: turn into macrophages (dynamic scavengers within the body) Inflammation: 2nd: skin: 1st, phagocytes: 2nd, b&t cells: 3rd, hydrochloric acid: 3rd. Mucous acts like a trap to trap pathogens in respiratory system. A general antibiotic can wipe out natural flora that creates acid that kills off candida albicans.
