BIOL 101 Lecture Notes - Lecture 20: Cell Cycle Checkpoint, Pyrimidine Dimer, Oncogene

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13 Nov 2016
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On sequence level during dna replication (polymerase) If damage is irreparable cell self destructs itself. If it can survive, a new allele is formed. When a mutation changes a protein that affects the function of a cell (possible. Reduced through fruits, sunscreen, maintaining a healthy weight. Tumor is large mass of uncontrolled cells. Physical or chemical agent we interact with. Allow for diversity and evolution by natural selection. Breaking hydrogen bond of t a causing 2 t nucleotides to bind together. Regulate progression to ensure each stage is accurately completed. Get from virus or mutation of proto-oncogene. Inhibit cell division normally mutations can cause uncontrolled cell growth. Either repair damage or direct cell to death (apoptosis) Develop at a younger age because you accumulate mutations faster. Not associated w inherited mutations but can be increased by brca cancer. Stretches of dna at end of chromosome to prevent loss of vital base pairs. Adds new bp"s to end of telomere.

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