BIOLOGY 101 Lecture Notes - Lecture 24: Allele Frequency, Zygosity, Gene Duplication

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14 Dec 2016
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Microevolution: change in allele frequency with time: happens over a few generations (1-2, macroevolution: change between species. Amount: heterozygosity: having different alleles at a gene locus, average heterozygosity: percentage of loci that are heterozygous across genome in a typical individual. Ex: drosophila is heterozygous t 14% of loci, yet only 1% of the nucleotides differ. Source of new alleles: mutation: sequence change that forms a new allele, gene duplication: new copies can serve a new purpose, immigration: inflow of existing alleles. Shuffling existing alleles: sexual reproduction: mixes alleles in each generation. Natural selection: enhanced growth, survival and reproduction lead to changes in allele frequencies. Sexual selection: enhanced mating success leads to changes in allele frequencies. Genetic drift: random shifts in allele frequencies. Founder effect: random shifts as a small new population arises from a large one. Bottleneck effect: random shifts as a recovering population grows from small to large. Gene flow: exchange of alleles among populations y immigration of individuals.

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