MICROBIO 101 Lecture Notes - Lecture 28: Bone Marrow, Natural Killer Cell, B Cell
28 Nov 2016
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Document Summary
High concentration of b cells and t lymphocytes: lymphatic organs. Where lymphocytes become immunocompetant (cells are capable of launching an immune response cells must be mature: red bone marrow (t and b made here; only b immunocompetant here immature t cells travel to the thymus and mature there) Long bones, flat and irregular bones: thymus gland (t lymphocytes travel here and then become immunocompetant) Get imbedded in secondary lymphatic organs and tissues. For all of these, we will have to launch an immune response. First, second, and third line of defense: nonspecific/innate defenses. Don"t develop a memory here (if you come across same virus repeatedly, Immediate response your body does the same thing, nothing specific because it doesn"t remember/recognize the pathogen: first line of defense. Gastric juice: acidic (ph = 1 or 2) Occurs if foreign body makes it past first line of defense. Interferons: produced by viral-infected cells, diffuse to nearby cells, interferes with viral replication.
