BIOLOGY 253 Lecture Notes - Lecture 15: Enzyme Kinetics, Insulin Receptor, Reaction Rate

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Unit goals: understand the function of an enzyme in a cell, analyze the kinetics of an enzyme using km and vmax. Free energy: measuring how much molecules are moving in space. Change in bond energy (release of heat, heat disorder) Delta g measures how far away from equilibrium a reaction is: excess x over y will compensate for the slow rate of the reverse reaction. Y=x or y>x, then delta g is less than zero (delta g < 0) Y<0), energetically unfavorable. Change in free energy determines whether a reaction will occur: Chemical reaction will only proceed if it results in a net increase in disorder (negative delta g) Spontaneous reactions: delta g < 0 (negative delta g), g products g reactants = delta g less than zero. Enzymes reduce the energy required to initiate spontaneous reactions.

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