BSCI 2201L Lecture Notes - Lecture 99: Antiviral Drug, Polyadenylation, Hepatitis C Virus
6 Apr 2016
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Document Summary
This paper review report is intended to explore the molecular mechanisms of hiv pathogenesis. Since the hiv/aids epidemic exploded around the end of the last century, a lot of research effort has been going to finding a vaccine for hiv and developing antiviral drugs that prevent the virus from hijacking cell machinery. This requires understanding how the virus works in the cell in order to develop effective ways for intervening in the virus pathogenic pathway. In this paper, i will start with exploring articles about hiv pathogenesis in general. I will attempt to understand two things: how does the virus interact with the host cell, and how can it evade innate immune responses. Then i want to shift my attention to intrinsic methods that the cell uses to evade the effects of hiv and dismantle the viral capsid before it replicates.
