BIOL 151 Lecture Notes - Lecture 13: Homologous Chromosome, Gene Duplication, Deoxyribose
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Spontaneous: occurrence by chance in the absence of any assignable cause. For individual nucleotides, mutation is a rare event: the highest rates of mutation per nucleotide per replication are found among. Rna viruses and retroviruses: certain nucleotides are especially prone to mutation and can exhibit rates of mutation that are greater than the average by a factor of 10 or more. Point mutations are changes in a single nucleotide: most dna damage or errors in replication are immediately removed or corrected by specialize enzymes in the cell. If a change in dna is to become stable and subsequently inherited through mitotic or meiotic cell divisions, it must escape correction by the. Dna repair systems: a mutation in which one base pair is replaced by a different base pair is called a. Point mutations that cause amino acid replacements are called. Nonsynonymous (missense) mutations: individuals who inherit two copies of the mutant globin gene that specifies the.