BCHM 3114 Lecture Notes - Lecture 10: Pyruvate Dehydrogenase, Acetyl-Coa, Decarboxylation

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5 Nov 2018
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Pyruvate and citric acid cycle (cac: draw a schematic diagram of a mitochondrion with all membranes and spaces labeled, indicate where the reactions of glycolysis, pyruvate decarboxylation, and the cac take place in human cells. Glycolysis occurs in the cytoplasm of all cells, pyruvate decarboxylation occurs in the mitochondira, and. Cac takes place in the matrix of the mitochondria: write the net reaction for the generation of acetyl-coa from pyruvate. Recognize that this involves coupled decarboxylation and oxidation reactions. Pyruvate and citric acid cycle (cac: explain how step 2 of the cac acts as a set up reaction for oxidative decarboxylation reactions in step. Pyruvate and citric acid cycle (cac: given the oxidized intermediate in step 3, indicate the movement of electrons that occurs upon decarboxylation. Look at picture above (intermediate: recognize the chemical similarity between oxidative carboxylation"s in step 3 of the cac and in the reaction of pyruvate of acetyl- coa.

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