Schizophrenia disrupts perceptions of the world, thought, speech, movement, and almost every other aspect of daily functioning. Usually chronic with a high relapse rate; complete recovery from schizophrenia is rare. Schizophrenia is a complex syndrome that has been recognized for centuries. Society often devalues these individuals and they are more likely to be stigmatized and discriminated against than those without schizophrenia. This catastrophic disorder takes a tremendous emotional toll on everyone involved. In addition to the emotional costs, the financial drain is considerable. The annual cost of schizophrenia in the us is estimated to exceed billion when factors such as family caregiving, lost wages, and treatment are considered. Because schizophrenia is so widespread, affecting approximately 1 in every 100 people at some point in their lives, and because its consequences are so severe, research on its causes and treatment has expanded rapidly. Melancholy, he outlined a description of the symptoms of schizophrenia.