BIO 440 Lecture 1: Human Genetics Lecture 1 notes

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Calico and tortoiseshell cats always are: heterozygous for the x-chromosome locus o, have one o allele (black) and one o allele (orange), are female. * patches of their fur express o or o depending on which x is inactivated. Luckily one copy of the x chromosome is enough for males, however there is a complication. If the x chromosome that the male inherits has a defective gene, there"s no wild type allele to cover up for it. So since males only have one x chromosome and it common for defective genes to show their traits because there is no other allele to mask it or cover it up. Only one allele of each x-linked gene (they are hemizygous: haploid for all genes on this chromosome)

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