HLT 3400 Lecture 3: Pharm Chart Drug Study Guide

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Alzhei(cid:373)er"s; glau(cid:272)o(cid:373)a, mg, nerve gas exposure; used as cholinergic agonists a neuromuscular blocker. Structurally similar to ach; the drug interacts with muscarinic receptors to cause body responses similar to pns stimulation. Pyridostigmine works by inhibiting action of ache at cholinergic receptors and allows ach to accumulate. Pns effects such as increased salivation, abd cramping, sweating, flushing, miosis, blurred vision, n/v; can have orthostatic hypotension with possible syncope, bradycardia, reflex tachycardia, complete heart block, and acute bronchospasm. Will enhance pns response so will have increased peristalsis, bronchoconstriction. Treatment of eye procedures (dilates eyes), suppress gastric acid (pud) cardiac rhythm disorders (increases hr), adjunct of. Drugs that block receptors at cholinergic synapses in the pns and at a. They contract bronchial smooth muscle; should not take if have gi or gu and others that end obstruction, with chol. Aricept, exelon, cognex. donepezil (aricept), riastigmine (exelon); neostigmine (prostigmin) for symptomatic tx of. Copd, mi, and with those with hyperthyroidism or cvd.

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