BIO130H1

Molecular and Cell Biology

University of Toronto St. George

One of the goals of modern biology is to understand how the basic building blocks of life give rise to biological form and function. This course provides students with a common lexicon to understand the key principles and concepts in molecular and cell biology, with a focus on how the building blocks of life lead to functioning cells. (Lab Materials Fee: $10). Lab coat and safety glasses are required for use in laboratories; students are responsible for purchasing these items (approximate cost is $25).
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| Kenneth Yip
BIO130H1- Final Exam Guide - Comprehensive Notes for the exam ( 177 pages long!)

[BIO130H1] Comprehensive Winter guide including any lecture notes, textbook notes and exam guides.find more resources at oneclass.com ...

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BIO130H1- Final Exam Guide - Comprehensive Notes for the exam ( 62 pages long!)

[BIO130H1] Comprehensive spring guide including any lecture notes, textbook notes and exam guides.find more resources at oneclass.com BIO130 FINAL (Cellular Form and Function) 2016-03-09 12:3...

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BIO130H1- Final Exam Guide - Comprehensive Notes for the exam ( 156 pages long!)

[BIO130H1] Comprehensive winter guide including any lecture notes, textbook notes and exam guides.find more resources at oneclass.com Introduction to Cells and Diversity Tree of ...

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Kenneth Yip
[BIO130H1] - Final Exam Guide - Ultimate 33 pages long Study Guide!

[BIO130H1] Comprehensive Final Exam guide including any lecture notes, textbook notes and exam guides.find more resources at oneclass.com Typical Model Organisms -E.Coli = prokaryotic cell -Yeast = eukaryotic cell -A...

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Exam Solutions for BIO130H1

BIO130H1 Study Guide - Fall 2018, Quiz - Helicase, Alpha Helix, C-Peptide
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TEXTBOOK QUIZ #1 1. A group of molecular cell biologists are attempting to synthesize a compound to minis the effects of a well-known hormone that affects digestion. They would like your advice about how to go ab...

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BIO130H1 Study Guide - Fall 2018, Midterm - Cycloheximide, Chloroplast Dna, Metabolome
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1. Which of the following correlates the most with genome size? a. An organisms size. b. The number of repeated sequences. c. An organisms complexity. d. The number of genes encoding proteins....

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BIO130H1 Study Guide - Fall 2018, Midterm - Rna Polymerase Ii, Cleavage And Polyadenylation Specificity Factor, Viral Vector
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1. The following statements describe different aspects of mRNA processing and maturation in the nucleus of eukaryotic cells. Which of these statements is FALSE? a. The first step in capping the 5 end of mRNAs is to...

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All BIO130H1 Materials | Spring 2016

BIO130H1 Final: Complete and Comprehensive 111 Page Final Exam Study Guide - Winter 2016
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BIO130H1 – Molecular and Cell Biology Final Exam Study Guide University of Toronto St. George – Winter 2016 BIO130 – Lecture 1 – Introduction The BIO120 Teaching team  Prof...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 24 - Blastocyst, Umbilical Cord, Cardiac Muscle
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BIO130 – Lecture 24 – Later Stages of Mitosis Thursday, April 7 , 2016 Chromosome attachment to microtubules - Green, yellow, and brown parts are all kinetochore protein o Inner kinetochore bind ...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 23 - Prometaphase, Pericentriolar Material, Phosphorylation
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BIO130 – Lecture 23 – The Cell Cycle Monday, April 4 , 2016 Cell Division - Not all cells in a culture divide at the same times - Very few cells divide at a given time - Individual chromosomes become visib...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 22 - Adherens Junction, Tight Junction, Basal Lamina
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BIO130H1 - Lecture 22 – Junctions Thursday, March 31 , 2016 In polarized epithelial cells: - Junctions are arranged in a specific order - Other types of cells can have junctions in diffe...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 21 - Basal Lamina, Hyaluronic Acid, Epithelium
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BIO130 – Lecture 21 – Tissues and ECM Monday, March 28, 2016 Preamble - In multiple sclerosis, the fatty myelin sheaths around the axons of brain and spinal cord cells are damaged - 2-150 in 100,000 peop...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 20 - Atp Hydrolysis, Kinesin, Dynein
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BIO130 – Lecture 20 – Actin Filaments Thursday, March 24 , 2016 Nerve Cells - Nerve cells in your spinal cord extend to your finger tips o These neurons can be a meter long - Problem: how does neur...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 19 - Mitosis, Interphase, Hydrolysis
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BIO130 - Lecture 19 – Cytoskeletons Monday, March 21 , 2016 Preamble - Pacific yew tree o Scientists harvested the bark, found compounds like paclitaxel  Paclitaxel is useful for canc...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 18 - Golgi Apparatus, Endoplasmic Reticulum, Signal Peptidase
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BIO130 – Lecture 18 – Signals and Sorting March 17 , 2016 Professor Yip’s Work (not on exam) Method #1: Compound Screening - It would take too many scientists to keep track of, store, move, and test millions ...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 17 - Cell Membrane, Endomembrane System, Golgi Apparatus
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BIO130 – Lecture 17 – Intracellular Compartments Intracellular Compartments - Hepatocyte o Involved in detoxification - Various organelles within a hepatocyte take up differing volumes within...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 16 - Resting Potential, Antiporter, Chlorine
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BIO130 – Lecture 16 – Pumps and Transport th March 10 , 2016 Preamble - Cystic fibrosis is a recessive genetic disease that causes progressive disability and early death - Difficulty breathin...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 15 - Blood Vessel, Cooperative Binding, Glut4
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BIO130 –thecture 15 – Membrane Transport March 7 , 2016 Outline - Permeability of lipid bilayer - Passive and active transport - Classes of membrane transport proteins o Uniporters ...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 14 - Prenylation, Photobleaching, X-Ray Crystallography
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BIO130 – Lecture 14 rdCell Membranes Thursday, March 3 , 2016 Preamble - Phospholipids form a bilayer in water - Many proteins insert into this membrane - Scientists are using these techniques to improve c...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 13 - Saccharomyces Cerevisiae, Extracellular Matrix, Lysosome
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BIO130 – Lecture 13 – Cellular Form and Function Professor Yip’s Introduction Drug Discovery Research - Identifying, synthesizing, developing, and studying new molecules that can be used as medications to t...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 12 - Aminoacyl Trna Synthetase, Aminoacyl-Trna, Peptidyl Transferase
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BIO130 – Lecture 12 – Translation Thursday, February 25 , 2016 Codon Redundancy - Redundant (also called degenerate) means a single amino acid can have several corresponding codons o Except ...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 11 - Rna Polymerase Ii, Garland Science, Consensus Sequence
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BIO130 – Lecture 11 – Processing and Termination Monday, February 22, 2016 Recall - Before reading week, we were discussing: o RNA processing - Already discussed promoters and initiation factors ...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 10 - John Wiley & Sons, Rna Polymerase Ii, Transcription Factor Ii A
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BIO130 – Lectthe 10 - Transcription Part II February 11 , 2016 Introduction - Special mushroom: aminita phalloides o Relevant characteristics to lecture o Produces a toxin that binds eukary...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 9 - Ribose, Cytoplasm, Chromosome
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BIO130 – Lecture 9 – DNA Errors Continued th February 8 , 2016 Strand-directed Mismatch Repair - In eukaryotes: o Post-polymerase error repair process o Initiated by detection o...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 8 - Okazaki Fragments, Chromosome, Telomerase Rna Component
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What We Lose With Age Cell Chromosome Cell As cells divide over time Telemeres. telomeres shorten, and eventually cell division stops end caps that protect chromosome What We Lose With Age Cell Chromosome Cell As cells di...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 7 - Helicase, Dna Replication, Dna Ligase
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BIO130 – Lecture 7 – DNA Replication st February 1 , 2016 Overview of DNA Replication Procedure 1) Separate DNA strands 2) Synthesize DNA 3) Proofread newly synthesized DNA DNA Synthesis Ingredien...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 6 - Histone H2B, Nucleosome, Nuclear Membrane
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INTERPHASE Chromatin PROPHASE spindle Centrosomes Chromatids of Nucleolus Y Nuclear envelope Aster INTERPHASE PROPHASE PROMETAPHASE TRANSITION Daughter chromosomes Equatorial plate TELOPHASE ANAPHASE METAPHASE H2A H2B 10 n...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 5 - Naegleria, Genome Size, Mitochondrion
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BIO130 Lecture 5 Genomes th January 25, 2016 Human Genome 3 billion base pairs per genome One maternal and one paternal genome = you 25,000 genes spread across 23 chromosomes XX female, XY male Genome Size Genomes can com...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 4 - Opioid Peptide, Amine, Proline
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BIO130 Lecture 4 Introduction to Protein Structure January 21, 2016 Mutational Steps Between Codons what is the minimum number of mutational steps between amino acids? o1 step=1 nucleotide change o mutations between codons...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 3 - Nucleotide, Nucleic Acid Nomenclature, Ribose
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BIO130 Lecture 3 DNA and RNA Monday, January 18, 2016 Three Parts of A Nucleic Acid phosphate group sugar oribose or deoxyribose base oA, T, C, G, or U Bases two types: purines and pyrimidines purines: guanine and adenine ...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 2 - Archaea, Metabolome, Ribosomal Rna
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BIO130 Lecture 2 Cells and Information Flow Tree of Life prokaryotes grouped in two lineages, bacteria and archaea three groups split from some kind of last universal ancestor bacteria also called eubacteria eucarya is ano...

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BIO130H1
Kenneth Yip
BIO130H1 Lecture Notes - Spring 2016, Lecture 1 - News1, Dna Replication, Cell Theory
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BIO130 Lecture 1 Introduction The BIO120 Teaching team thth Prof Melody Neumann January 11 to February 25 Reading Week thth Prof Ken Yip February 29 to April 7 Prof Ken Yip evening section Prof Melody Neumann course and l...

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BIO130H1
Kenneth Yip
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