BIO230H1 Lecture Notes - Lecture 1: Dna Microarray, Transcriptome, Human Genome

Bio230 lec 1 prokaryotic transcriptional regulation sep 11. Cell wall for tough protective outer coat but optional, and produce toxin. Microskeletons (

BIO230H1 Lecture Notes - Lecture 2: Chromatin, Histone Acetyltransferase, Phosphorylation

Bio230 lec4 eukaryotic gene regulation sep 18. Topics: eukaryotic transcriptional activation, eukaryotic transcriptional repression. Various types of r

BIO230H1 Lecture Notes - Lecture 2: Repressor, Positive Feedback, Synthetic Biology

Bio230 lec 3 prokaryotic transcriptional regulation sep 18. Topics: prokaryotic gene regulation (recap, bacteriophage lambda, synthetic biology, transc

BIO230H1 Lecture Notes - Lecture 3: Exon Junction Complex, Alternative Splicing, Polyadenylation

Bio230 lec 5&6 post-transcriptional regulation sep 25. Topics: rna processing, rna nuclear export, mrna quality control, mrna stability. Translation ca

BIO230H1 Lecture Notes - Lecture 4: Proteasome, Creb-Binding Protein, Phosphatase

BIO230H1 Lecture Notes - Lecture 5: Extracellular Matrix, Membrane Protein, Cell Wall

Bio230 lec 9&10 protein sorting oct 9. Topics: overview - key concepts, protein synthesis, protein sorting to different locations, nucleus, mitochondri

BIO230H1 Lecture Notes - Lecture 6: Golgi Apparatus, Glycosylation, Transmembrane Protein

Bio230 lec 11&12 intracellular vesicular transport oct 16. Topics: glycosylation, main focus on n-linked glycosylation, vesicular transport. Overview: 

BIO230H1 Lecture Notes - Lecture 7: Endosome, Neuron, Endocytosis

Bio230 sec2 lec 1 cell and tissue self-organization oct 23. For example, both epithelial cells and nerve cell are polarized cells. Some would go to the

BIO230H1 Lecture Notes - Lecture 8: Basal Lamina, Tight Junction, Cell Adhesion

Bio230 s2 lec2 cell adhesion &amp; tissue morphogenesis oct 30. Topics: formation of large and stable organisms from small fragile cells, establishment

BIO230H1 Lecture Notes - Lecture 10: Notch Signaling Pathway, Cellular Differentiation, Morphogen

Bio230 s2 lec3 cell differentiation &amp; structure maintenance nov 13. Cell differentiation: extrinsic mechanisms associated with symmetric division t

BIO230H1 Lecture Notes - Lecture 11: Small Molecule, Quorum Sensing, Nuclear Receptor

Bio230 s2 lec4 cellular signaling &amp; small molecules nov 20. Cellular signaling: communication to develop and maintain multicellular organisms, unic

BIO230H1 Lecture Notes - Lecture 12: Epidermal Growth Factor Receptor, Insulin Receptor, Cell Membrane

BIO230H1 Lecture Notes - Lecture 13: Gel Electrophoresis, Phosphatidylserine, Apoptosis

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The genome is the "book of life," providing instructions to construct an organism. This course introduces genome biology and explores how the building blocks of life are networked into functioning organisms. We will investigate how cells perceive internal and external cues, how gene expression is shaped by this perception, and how these events give rise to tissues, organs, and whole organisms. (Lab Materials Fee: $20). Lab coat and safety glasses are required for use in laboratories; students are responsible for purchasing these items (approximate cost is $25).

From Genes to Organisms

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