1
answer
0
watching
197
views
24 Sep 2018
You have discovered a new gene âXâ that appears to be regulated by 3 transcription factors (E2F, SP-1 and C/EBPa). Another gene âYâ appears to also be regulated by these same proteins. Both genes are involved in cell cycle initiation but gene Y is expressed later in the cell cycle than gene X.
The DNA sequence at the promoter region is GCGCCAATGTGCTGACAGTTAATTAGGGCTA
The known DNA consensus sequence for each Transcription Factor is:
E2F â GCCAATGTGCTGA
SP-1 â GCTGACAGTTAA
C/EBPa â ACAGTTAATTAGG
Design a series of experiments that will investigate the regulation of Gene X and Gene Y. All proteins and gene sequences are known. You have a large well-funded lab.
You have discovered a new gene âXâ that appears to be regulated by 3 transcription factors (E2F, SP-1 and C/EBPa). Another gene âYâ appears to also be regulated by these same proteins. Both genes are involved in cell cycle initiation but gene Y is expressed later in the cell cycle than gene X.
The DNA sequence at the promoter region is GCGCCAATGTGCTGACAGTTAATTAGGGCTA
The known DNA consensus sequence for each Transcription Factor is:
E2F â GCCAATGTGCTGA
SP-1 â GCTGACAGTTAA
C/EBPa â ACAGTTAATTAGG
Design a series of experiments that will investigate the regulation of Gene X and Gene Y. All proteins and gene sequences are known. You have a large well-funded lab.
Patrina SchowalterLv2
25 Sep 2018
