indicate whether you think the statements are true or false, and explain your reasoning. In each of your answers, provide 1-2 specific examples that support your position. (Each of your four answers is worth five points):
A) Memory cells require fewer distinct signals to be activated than naiÌve cells require.
B) Both B cells and T cells undergo âclonal selectionâ after they are activated by antigen.
C) A B cell is only able to present antigen to a T cell that includes the epitope to which the
B cellâs receptor bound.
D) T cells can recognize peptide antigens in the context of MHC I and MHC II regardless of
whether they are Thelper or Tcytotoxic cells.
E) B cells and T cells can both still make productive antigen receptors via V(D)J
recombination even if no P-nucleotides are introduced during the process.
F) Allelic exclusion takes place when a naiÌve T or B cell encounters its specific non-self antigen for the first time and determines whether or not to become activated.
G) B cells have more chances to make a productively rearranged antigen receptor than T cells do.
H) A majority of immature T cells developing in the thymus will survive both positive and negative selection.
I) The reason why T cells are the only type of white blood cell that requires maturation in a specialized organ outside the bone marrow is because they are the only ones that must have antigen processed and presented to them before they can be activated.
indicate whether you think the statements are true or false, and explain your reasoning. In each of your answers, provide 1-2 specific examples that support your position. (Each of your four answers is worth five points):
A) Memory cells require fewer distinct signals to be activated than naiÌve cells require.
B) Both B cells and T cells undergo âclonal selectionâ after they are activated by antigen.
C) A B cell is only able to present antigen to a T cell that includes the epitope to which the
B cellâs receptor bound.
D) T cells can recognize peptide antigens in the context of MHC I and MHC II regardless of
whether they are Thelper or Tcytotoxic cells.
E) B cells and T cells can both still make productive antigen receptors via V(D)J
recombination even if no P-nucleotides are introduced during the process.
F) Allelic exclusion takes place when a naiÌve T or B cell encounters its specific non-self antigen for the first time and determines whether or not to become activated.
G) B cells have more chances to make a productively rearranged antigen receptor than T cells do.
H) A majority of immature T cells developing in the thymus will survive both positive and negative selection.
I) The reason why T cells are the only type of white blood cell that requires maturation in a specialized organ outside the bone marrow is because they are the only ones that must have antigen processed and presented to them before they can be activated.
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