when using quantitative trait loci mapping, why is it significant to find linkage between a trait of interest and a genetic marker?
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Question 1: Why are marker alleles useful to study even though they do not actually affect the traits being studied? Explain in your own words the logic underlying QTL mapping.
Multiplie choice: The genetic signature of recent positive selection on a locus is ...
In lecture you were shown hybrid crosses involving 2 and 3 loci. If you were to conduct a hybrid cross with 4 loci, what would the dimensions of your Punnett square be? If the alleles were purely codominant and additive to yield a quantitative phenotypic trait, how many different phenotypic classes would you expect? Explain your reasoning. Hint: You do NOT need to actually construct a Punnett square to figure out the answer and in fact it is not recommended to construct a Punnett square. Look at the similar example of a polygenic trait with 3 loci from your online activities.
You are interested in two phenotypic traits, one has a heritability of 0.8 and the other has a heritability of 0.4. You want to find the approximate location of genes controlling these phenotypes using a linkage mapping approach. But, you only have enough grant money to do this for one trait. Which one would you have more chance of success with and why? (Hint: the equation for heritability is, H2 = VG / VP) (3 marks) â