Question

In a cohort study participants are classified according to exposure status (e.g. risk factor status) at baseline (e.g. upon enrollment in the study), and then are followed – up over time to ascertain an outcome(s) (e.g. disease). Key features of the cohort study design: it can be used to find multiple outcomes (e.g. diseases) from a single exposure, well suited for studying rare exposures, ensure temporality (i.e. that exposure occurs before the observed outcome).

What is an example of a single exposure that can cause more than one type of disease?

What is an example of a disease caused by a rare exposure?

Why is temporality important?