1. GAPs (GTPase activating proteins) act on G proteins toâ¦
A.
stimulate GTP hydrolysis, thereby turning the G protein âon.â
B.
stimulate GTP binding, thereby turning the G protein âoff.â
C.
stimulate GTP hydrolysis, thereby turning the G protein âoff.â
D.
stimulate GTP binding, thereby turning the G protein âon.â
QUESTION 2
1. Transautophosphorylation occurs on
A.
guanylyl cyclases
B.
receptor tyrosine kinases
C.
transmembrane scaffolds
D.
G protein-coupled receptors
QUESTION 3
1. Local mediators are ligands that are involved in
A.
paracrine signaling
B.
synaptic signaling
C.
contact-dependent signaling
D.
endocrine signaling
QUESTION 4
1. Which of these are NOT signal termination mechanisms?
A.
Release of ligand from its receptor
B.
G protein reformation (Gα + Gβγ = Gαβγ)
C.
G protein hydrolysis of GTP (G-GDP)
D.
Second messenger release
QUESTION 5
1. A lipid-soluble ligand would be expected to bind to a
A.
Second messenger
B.
transmembrane receptor
C.
G protein coupled receptor
D.
nuclear receptor
QUESTION 6
1. Which amino acid is NOT mainly phosphorylated by a protein kinase?
A.
threonine
B.
serine
C.
tyrosine
D.
lysine
1. GAPs (GTPase activating proteins) act on G proteins toâ¦
A. | stimulate GTP hydrolysis, thereby turning the G protein âon.â | |
B. | stimulate GTP binding, thereby turning the G protein âoff.â | |
C. | stimulate GTP hydrolysis, thereby turning the G protein âoff.â | |
D. | stimulate GTP binding, thereby turning the G protein âon.â |
QUESTION 2
1. Transautophosphorylation occurs on
A. | guanylyl cyclases | |
B. | receptor tyrosine kinases | |
C. | transmembrane scaffolds | |
D. | G protein-coupled receptors |
QUESTION 3
1. Local mediators are ligands that are involved in
A. | paracrine signaling | |
B. | synaptic signaling | |
C. | contact-dependent signaling | |
D. | endocrine signaling |
QUESTION 4
1. Which of these are NOT signal termination mechanisms?
A. | Release of ligand from its receptor | |
B. | G protein reformation (Gα + Gβγ = Gαβγ) | |
C. | G protein hydrolysis of GTP (G-GDP) | |
D. | Second messenger release |
QUESTION 5
1. A lipid-soluble ligand would be expected to bind to a
A. | Second messenger | |
B. | transmembrane receptor | |
C. | G protein coupled receptor | |
D. | nuclear receptor |
QUESTION 6
1. Which amino acid is NOT mainly phosphorylated by a protein kinase?
A. | threonine | |
B. | serine | |
C. | tyrosine | |
D. | lysine |