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23 Nov 2019

which protein must be phosphorylated before it degraded?

a) anaphase inhibitor

b) cyclin

c) S phase inhibitor

d) cyclin kinase

. ____ is an activator of p21 transcription if there is DNA damage?

a) SPF

b) Myc

c) E2F

d) p53

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11 Nov 2019
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Related questions

1. MPF( M phase promoting factor) is best described as a?

a. cyclin

b. protein kinase

c. a complex of cyclin and protein kinase

d. a complex of a specific cyclin and a specific proteinkinase.


2. Which of the following changes in a normal cell wouldincrease the likehood that the cell would become malignant?

a. loss of p53, activation of Ras, activation of caspases.

b. Loss of retinoblastoma protein, activation of ERB-13 (agrowth factor receptor, loss of DNA repair protein

c. high levels of camp, loss of insulin receptor, high levels ofCa++, loss of E. cadherin (a cell adhesion molecule)



Which of the following statements correctly describes p53?

A) Cell division stops until p53 binds to DNA and repairs the damage

B) It is a membrane receptor that binds to growth factors such as EGF

C) Activation of p53 leads to inhibition of the cyclin-CDK complexes

D) p53 binds to pre-replication complexes promoting the transition from G1 to S phase

E) p53 is an example of an oncogene, and its expression causes uncontrolled cell division

(A) What is the correct order of cell cycle phases? Select one:

a. G1 to S to G2 to M phase b. M to G2 to S to G1 phase c. none of these d. G1 to G2 to S to M phase e. G1 to M to S to G2 phase

(B) What cyclin-cdk complex is critical in mitosis? Select one:

a. Cyclin E - cdk2 b. cyclin E - cdk1 c. cyclin A - cdk 2 d. cyclin B - cdk1 e. cyclin D cdk 4

(C) Which of the following proteins is progressively phosphorylated throughout the cell cycle from G1 through to M phase? Select one:

a. E2F1 b. pRb c. RNA polymerase II d. cyclin D e. cyclin B

(D) An antibody generated from a mouse hybridoma cell line is called a mouse ________. Select one:

a. anticlonal antibody b. polyclonal antibody c. synclonal antibody d. none of these answers e. monoclonal antibody

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