BIO230H1 Lecture Notes - Lecture 8: Retinoid, Resting Potential, Response Element
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BIO230H1 Full Course Notes
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Document Summary
Nitric oxide gas signals by directly regulating the activity of specific proteins. Extracellular signal molecules and bind on the surface of the target cell. Nitric oxide (no) which acts the signal molecule in both animal and plants. Many types of nerve cells use no more directly to signaling. No synthase (nos): no is made by the deamination of amino acid arginine. Nos is found in the nerve and muscle: nnos. No enzyme for the active site (guanylyl cyclase) can turn to gtp to gdp. Carbon monoxide uses it in a similar way. Signal molecules include steroid hormones, thyroid hormone, retinoids and vitamin d. Nuclear receptor superfamily: receptors are structurally related. There are transcriptional response involve multiple steps. Primary response: protein products of these gene in turn activate other genes to produce a delayed: secondary response. Many types of cells by the nature of the signal molecule. Hydrophobic signal molecule and have receptors that bind to a lignad.
