BIO230H1 Lecture Notes - Lecture 6: Retinal Pigment Epithelium, Stereocilia, Chemokine
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BIO230H1 Full Course Notes
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Interfollicular epidermis is multilayered epithelium composed of keratinocytes. There are basal cells are several layers of prickle cells. Granular layer barrier to the movement of water and solutes. The outer cells are squames filled with keratin. Differentiating epidermal cells express a sequence of different genes as they. Kertinocyte in the basal layer is transformed. Terminal cell differentiation: process in precursor cell acquires its final specialized characteristics and usually permanently stops dividing. Stem cells in the basal layer provide for renewal of the epidermis. Humans renew the cells in the basal side. When cell divides it can retain a stem cell to commit it to terminal differentiation. Stem cells can divide into many different tissues. The two daughters of a stem cell do not always have to become different. Division of a stem cell could generate two initially similar daughter cells with two daughter cells. There is a renewal patch that can occur if the epidermis is damaged.
