Microbiology and Immunology 2500A/B : Virology Lecture Notes

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Kang lecture 1: an introduction to molecular biology. Virus is unique as some have genome in the form of rna. Human genome: 3. 3 billion base pairs, approximately 35, 000 genes, total length of dna: 1 x 1010 km. In humans, 23 pairs of chromosomes: contains dna, helps human genome reveal that there are 3. 3 billion base pairs which contain approximately 35, 000 genes. Most dna is in double stranded form, some viral dna exist as a single stranded form. Replication of dna is semiconservative direction of copy of dna is only in one direction synthesizes from 3" to 5". In order to copy this dna, it has to be unwind one strand goes up, and another strand goes down. Single stranded dna is copied to make double stranded dna (viral pathway) In the cell, double stranded dna is transcribed to make mrna which is translated to make proteins (cellular pathway) Unique property of viruses consist of rna in their genome.

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