BIOD29H3 Lecture Notes - Viral Matrix Protein, Natural Killer Cell, Cell Culture
10 Dec 2012
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Document Summary
The study of classification is known as taxonomy. Emerging pathogens are viruses we haven"t encountered or mutated virus that does not have a name. Classification is based on many things and can include geometrical information which we will not talk about. Viruses can have a single stranded genome so it depends on if they have a positive or negative strand. Baltimore classification system is intuitive and easy to understand. The sense" strand is the strand that is equivalent to the mrna. Negative stranded rna genome is bringing in the complimentary strand of rna and this strand is the mrna. There is a one-step difference between this and positive stranded rna. There are two strands but they almost always have dependent rna polymerase which uses the negative strand to make the mrna. Similarity between double stranded and negative stranded. (3 and 2) Energetically highly unfavorable to pull two strands apart and use one as a template therefore.
