BIOB51H3 Lecture Notes - Lecture 11: Point Mutation, Mutation Rate, Hemoglobin
14 Dec 2012
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A condition that affects the nerves in an area of the spinal cord called the anterior horn. These nerve cells become damaged, breaking the line between the brain and the muscles. As a result, the muscles can"t be used and become wasted. caused by point mutation: m. You can see this (the rate of a deleterious allele stays the same overtime) if the rate of loss due to selection = the rate of creation through mutation. For this we have the data to see whether the mutation of this gene leading to this phenotype is efficient to keep the allele frequency at equilibrium point. 1)relative fitnesses of genotype fitness of wild type 1. 0. The fitness of an individual is 1-the selection against them (sm) S is the selection coefficient ranges from 0 to 1 the closer it is to 0, the lower the selection against you (fitness of individual = fitness of wild type): equilibrium frequency of m.
