BIOL 300 Lecture Notes - Glycerol, Transfection, Protein Kinase A
15 Dec 2012
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Document Summary
Many components of the rtk pathway were identified using genetics and the compound eye of. Drosophila; this is because mutations in these genes are often viable, and they are very easily seen. In all insects, the eye is compound, meaning it"s made up of 600 or so smaller eyes, called ommatidia (each of which function as a separate eye, integrated by the brain) Each ommatidium is made of 8 photoreceptors, labeled as r1 r8; the ligand called boss (present on r8 cells, don"t need to remember the name) and the. In the wild type, we can see that cross sections of ommatidia stained to be able to see the neurons; we can indeed see all 7 of the neurons (r8 is too deep) At one point, some components of this pathway were identified (rtk, ligand, ras and raf), but we still needed to identify the downstream components which raf acted on.
