CSB327H1 Lecture Notes - Lecture 18: Elastic Fiber, Fibrillin, Elastin

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Csb327 lecture 18 notes elastic fibers and tissue resilience (december 3, 2012) 1 lecture topics: elastin is broadly distributed in tissues. 3 artery: do not memorize this structure, smooth muscle cells are contractile. If they are disregulated, they can form mvs and. In an artery, they are all lined with endothelium followed with bl then elastin. begin hardening of the arteries: the precision of the assembly of elastic fibers has to be tightly controlled. 4 internal elastic lamina of murine aorta, with associated endothelial cell and smooth muscle cell: how is elastin assembled and regulated, elastic fibers are abundant. Elastic fibers are a composite of more than just elastin: where you have high hydrostatic pressure, you will have a lot of elastin. The strength of the skin is based on the collagen composites. If you stretch a rubber band, there is some cross-linking that enables them to stay as a polymer.

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