BLG 144 Lecture Notes - Semiconservative Replication, Helicase, Dna Replication

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11 Jan 2013
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Nucleic acids carry the genetic code that determines the order of amino acids in proteins. Genetic material stores information, can be replicated, and undergoes mutations. Differs from proteins as it has phosphorus and no sulphur. Nucleotides are smaller units of long chains of nucleic acids. Each nucleotide has: a pentose sugar (deoxyribose in dna, ribose in rna, a phosphate group, an organic base which fall into 2 groups, Purines (double rings of c and n - bigger) Pyrimidines (single ring of c and n - smaller) Chains are directional according to the attachment between sugars and phosphate group. They are antiparallel which is essential for gene coding and replication. Dna molecule has 2 separate chains of nucleotides hold together by base pairing / dna normally twist into a helix (coil) / forms a double helix. Single chain (shorter than dna - lower molecular mass) Adenine, guanine and cytosine are the same: ribosomal rna (rrna)

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