BIOL 2P02 Lecture Notes - Antibiotics, Lipopolysaccharide, Brush Border
13 Jan 2013
School
Department
Course
Professor
Document Summary
Damage or destroy host cells - e. g. hiv, salmonella: organism is taken up by epithelial cells in the intestine. Host specific: ligand on pathogen must fit onto receptor proteins on host. Impaired absorption of water and salt from the gut. Some bacteria will cause all of the 3 ways above; some require a large number of bacteria for a disease; some will only a few number of bacteria. Microorganisms may enter the lymphatic system via tissue fluid and are carried around the body in this way. Ability of bacteria to cause disease relies on: location - what tissue is colonised, pathogenicity - how a bacterium cause disease. Infectivity - how easily a bacterium can enter the host cell. Invasiveness - how easily a bacterium or its toxin spreads within the body. Latent period: bacteria may lie inactive for up to 30 years and become active as primary. Inhaling droplets exhaled from a carrier during coughing causes the infection tuberculosis (tb)
