PHIL 3576 Lecture Notes - Smallpox, Putting-Out System, Cowpox
Document Summary
Evaluating the efficacy of a new drug by testing it on human is not new (dates back to the 10th century) 10th century records show testing the efficacy of poisons on prisoners (captive populations) 13th century- roger bacon- experimental science; said it was dangerous to perform experiments on human subjects. Human experimentation made most significant impact through edward jenner; Dairy farmers that contracted cow pox, were immune to small pox: many in this experiment died or developed harmful illnesses. Inject subjects with swine pox: after a week he injected them with small pox. *first human research subject was his two year old son (no results) Later tried first injecting an 8 year old boy with cow pox and then small pox and was successful. Alexis martin had a gaping wound on his stomach; beaumont used this opportunity to study gastric juices.