HSS 1100 Lecture Notes - Lecture 4: Endocarditis, Dental Surgery, Neisseria
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Most important gram positive cocci pathogen we will cover. The cellular arrangement of the round cells resemble a cluster of grapes (staphule) Dairy products (creamy sauces) are most vulnerable to s. aureus. Considered a "prototype" for successful pathogens; one of the most successful pathogens. Makes many toxic substances that allows it to overcome many barriers when it encounters the body. Blood clots helps protect the bacteria long enough so that it can survive and multiply. Among the many species of staph, only s. aureus produces coagulase. Coaguluse can be used as a test / screen to detect this bacteria. Enterotoxins (entero refers to the enteric system or the gut) causes troubles in the digestive system. Toxic shock syndrome toxin 1 can lead to toxic shock syndrome. Hemolysins break down rbcs that release nutrients / iron that bacteria can use to thrive. Cytotoxin (cellular toxin) affects / kills certain cells in the body. Exfoliative toxins affect skin and cause severe rashes.