ANSC 3120 Lecture : 6. Lipids.doc
24 Jan 2013
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Eg 18:0 steric acid or: deprotonated at stearate physiological ph. Polyunsaturated pufa : two or more double bonds. Where the first bond occurs 6th carbon. Why: methylene interrupted**, more stable than conjugated, conjugated pufa peroxide very rapidly. Required desaturase enzymes found in plants; so these fatty acids originate in diet as plant and algae oils. May be found concentrated in animal products: eg, -3 coldwater fish oil. Fatty acids deficiencies common: no, some conditions: Poor-total parental nutitrion (tpn) via iv historical. Proper composition of neural lipids (dha: -6 infants on low -3 formula. Essential fatty acid deficiency signs n-6 deficient. Overlap: a certain -3 fatty acid [epa] dampens eicosonoid signaling, preventing inflammation. Elongation pathways: 10% of fatty acids in grey matter, 35% of fatty acids in retina. Ai = 2-3% of dietary energy: each new double bond is 3 carbons further than the methyl end so designation doesn"t, elongation always at 2c + cooh end change.
