PHSI 208 Lecture Notes - Comorbidity, Cups, Iatrogenesis

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25 Jan 2013
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Relapse prevention is one of the most imp goals of long term mgt of s. relapse is both distressing and costly. Poor adherence to meds is a primary cause of relapse and re hospitalization. As high as 80% of ppl are unable or unwilling to take meds as directed. Approx 75% of ppl discontinued the assigned meds due to lack of efficacy, intolerability or both. Another reason for poor adherence is ppls poor insight into their disorder however problems related to accessing prescriptions, obtaining refills and simply forgetting to take meds play a role too. Nonadherent ppl with s are 5 times more like to relapse than those who adhere to prescribed regimens. They found a significant reduction in the replase rate among ppl who took the atypical antip. The average relapse rate with haloperidol was 23% whereas the rate for the group of 2nd generation drugs averaged only 15%.

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