BIOL 2050U Lecture Notes - Multiple Myeloma, Antibody, Thymus
Document Summary
Immune system- protects host from diverse microorganisms and products. Antigens-substances to which specific immune responses are made (diversity of responses) Antibodies-proteins that bind specifically to antigens (secreted by b-cells) Millions, b/c of special genetic mechanisms for the generation of diversity. Effector mechanisms-after recognition, deals with foreign antigen. (differs by pathogen) Memory-response to a pathogen is remembered to elicit a faster response if pathogen is encountered again. Slow to develop (few days vs. rapid replication rate of microbes) Keeps pathogen in check until the ai response matures (immune system evolves slower than microbes) Goals of layered immune system: skin and mucosol surfaces = barrier. Depends on tight junctions and secreted antimicrobial substances (muc, acid, defensins, lys, lipids, etc: innate immunity rapid response with little specificity to hold infection in check (days) Depends on phagocytic cells and complement : adaptive immun highly specific and effacious.
