BIOL 1000 Lecture Notes - Lecture 11: Centrosome, Dna Replication, Chief Operating Officer
31 Jan 2013
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Kdl receptors how does the process work: golgi to er, it is retrograde (backwards) Understand the idea that there are signals on proteins (aa"s that have a function) For glycoproteins, certain signals that tell it to go to the lysosyme. Structural sequences that tell other proteins what they"re going to do: nh3 ----- kdel (signal) coo- cop i with them. So based on charge and shape, they will bind to proteins on golgi so they fit in like an active site. The cop i proteins cause dimpling until bubbling causes popping off. Ph differences cause the structural changes and then it changes binding ability. Micelles vs. liposomes: micelle will be on exam. Sphere of fatty acids with non-polar interior. Protein b100 binds to ldl receptors on plasma membrane. It makes sure that it doesn"t go to the wrong cells. If a mutation occurs and it does go to the wrong cells, like heart, death!
