BIOL 1111 Lecture Notes - Mecha, Apoptosis, Ionophore
1 Feb 2013
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Cristae for surface area varying morphology, size, number, location depending upon cell type typically long thin tubules; tethered to cytoskeleton dynamic: constantly fusing/dividing (so mtdna can recombine) specialized pumps and carriers for inner membrane. Endosymbiont hypothesis: double-membrane (one mt, one plamsic) circular genome prokaryotic translation mech. unique genetic code. Atp (tca, oxphos) apoptosis lipid synth heme synth. Aa metabolism/synth urea degradation ion storage/homeostasis developmental pathways (cell fate) Disease: neuromuscular cardiomyopathies liver disorders aging cancer mtdna: 13 proteins (of 1000 total) rest must be imported from cytosol slightly different genetic code between organisms multi-subunit complexes encoded both by mtdna and nucleus. Peroxisomes single membrane varying number depending on cell type, cell conditions high protein concentration inside crystallization functions: produce h2o2 and degrade it to water and oxygen. B-oxidation of long fatty acids plasmalogen synth (neuronal phospholipid) lipid synth chol. synth bile acid synth assembly:
