PHGY 355 Lecture Notes - Transpulmonary Pressure, Intrapleural Pressure, Chronic Obstructive Pulmonary Disease
7 Feb 2013
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Airway dynamic compression large component of obstructive diseases you can not break free of your maximal output no matter what your respiratory system can easily handle increased demands. Ow limitation occurs when alveolar and pleural pressures become equal (cid:12254) Hyperin ation compensates for an obstructive disease (cid:12254) (cid:12254) causes excess lung volume meaning that the dynamic compression will be resisted. But this causes extra work needed for normal breathing changes causes by copd result in a narrow airway, making lung compression easier. Comparing diseased and normal flow-volume curves (cid:12254) (cid:12254) (cid:12254) (cid:12254) (cid:12254) Obstructive and restrictive diseases result in lowered maximum expiratory. Tlc decreases for restrictive due to a stiffer lung that cannot reach higher volumes. Ow limitation is decreased (cid:12254) this hyperin ation takes a lot of work container size in the early diseased state of an obstructive disease is roughly identical to the normal (cid:12254) bronchodilators improve the expiatory out ow of individuals with copd.
