BIOL 2020 Chapter Notes - Chapter 5: Decimal Mark, Activation Energy, Endergonic Reaction
Document Summary
5. 1 enzymes are powerful and highly specific catalysts. Proteolytic enzymes catalyze proteolysis (hydrolysis of a peptide bond) Specificity of an enzyme: due to precise interaction of the substrate with the enzyme. This precision is a result of the intricate 3d structure of the enzyme protein. Cofactor groups: 1 group=small organic molecules=coenzymes 2nd group=metals. 5. 3 free energy is a useful thermodynamic function for understanding enzymes. Consider delta g (change between products and reactants and activation energy. A reaction can take place spontaneously only if delta g is negative, exergonic. Equilibrium=no net change delta g is zero. Delta g depends only on free energy of the products minus reactants, depends. If positive endergonic on the path it takes. Delta g provides no information about the rate of a reaction. Delta g knot is the standard free energy change at 25 degrees celsius.
