BIOL 2020 Study Guide - Final Guide: Adrenergic Receptor, Signal Transduction, Cell Membrane
Document Summary
Ion channel linked receptors, g-protein linked receptors , enzyme linked receptions. And describe that class 3 e. g. which terminus is intra vs extracellular. Immune system receptor and protein, localized signals thru tissues and short lived, neurons signals over greater distance, sobule small molecules thru the blood for hormoneslast 3 have signal molecules first one doesn"t. Receptor on intracellular (enzymatic activity) intracellular mediators effector enzymes (can turn genes on) target proteins (second messengers) real pathways can bypass or add more steps. Mediated by neurotransmitters and ion channel (changes permeability of plasma membrane), indirectly regulates activity of separate membrane bound protein (activates enzyme) , functions as enzymes (protein kinases) (form dimers) 7 transmembrane receptors, 7 helices that span the membrane bilayer, and e. g. is smell, taste, vision c-terminus, n-terminus. Beta adrenergic receptor , 7tm receptor , conformational change inside cell. Heterotrimer (alpha, beta, and gamma subunits) subunit alpha binds gdp , other 2 bound to lipid anchors.
