BIOL 2020 Study Guide - Final Guide: Dihydroxyacetone Phosphate, Galactose, Galactitol
Document Summary
Transport proteins, glucose-6-phosphate by hexokinase because g6p cannot enter cells, and it destabilizes glucose , use atp. Fructose-6-phosphate (isomeration) fructose 1,6-biphosphate (phosphorylation by pfk uses atp) Dhap and gap (all turns into g3p in the end by aldose) 1,3-bpg (creates nadh, 1st oxidation- favorable,2nd joins carboxylic acid(phosphorylation) unfavorable) must be coupled to happen, intermediate has thioester. High in energy and has a great phosphoryl-transfer potential. Pyruvate (decarboxylation) needs thiamine-releases co2 acetaldehyde- reduction-releases nad+ ethanol no net nad anything, gets created and then used up. Fructose dhap, gap (both from liver) and also f6p from adipose. Phosphorylated to f1p split into glyceraldehydes and dihydroxyacetone phosphate -> glyceraldehydes goes to g2p. Regulation of pfk in the liver transferase doesn"t work) infants fail to thrive, vomit when drinking milk, cataracts form, accumulated galactose reduced to galactitol, water diffuse into lens, lots of milk drinking. Ratio of atp/amp, if falls glycolysis is stimulated.
