BLG 312 Lecture Notes - Cytosine, Guanine, Thymine

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Nucleic acids carry the genetic code that determines the order of amino acids in proteins. Genetic material stores information, can be replicated, and undergoes mutations. Differ from proteins as it has phosphorus and no sulphur. Made up of several chains of nucleotides. Dna and rna are types of nucleic acids. Sugar-phosphate backbone (ensures stability of the molecule: pentose sugar. Organic bases: purines (double rings of c and n - bigger) Guanine: pyrimidines (single ring of c and n - smaller) Made up of 2 separate chains of nucleotides hold together by base pairing: connected by weak hydrogen bonds, can easily be opened for replication, adenine-thymine has 2 h-bonds, cytosine-guanine has 3 h-bonds. Dna normally twist into a helix (coil) / forms a double helix: makes the molecule compact (store a lot in small space, protects from damage as base pairs are facing inwards.

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