BIOL 3020 Lecture Notes - Prefrontal Cortex, Temporal Lobe, Basal Ganglia
11 Feb 2013
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Molecular genetics it does not appear that the genetic predisposition to s is transmitted by a single gene; several multi or polygenic models remains viable. Alternative strategies for s vulnerability gene identification were and are needed. S research turned to the endophenotypic strategy . endophentoyupes are characteristics that reflect the actions of genes predisposing an indiv to a disorder even in the absence of a diagnosable pathology. Imp cuz indiv endophenotypoe are determined by fewer genes than the more complex s phenotype. Thus the complexity of genetic analyses would be reduced. Increasing evidence for an overlap in genetic susceptibility including s and bipolar disorder. Evaluation of the genetic data s is not complete due to genetics. S is defined by beh: it is a phenotype and thus reflects the influence of both genetics and enviro. Genetics predispose ppl to it and ten you need stress to bring it out.
