MCB 2050 Study Guide - Heat Shock Protein, Rna Splicing, Entertainment Uk

• School: University of Guelph
• Department: Molecular and Cellular Biology
• Course: MCB 2050
• Professor: Ray Lu

Document Summary

Eukaryotic gene expression can be regulated at the transcriptional, processing, or translational levels. In eukaryotes, genes are regulated in a spatial dimension. Multicellular organisms contain many diff cell types organized into tissues and organs. e. g. - particular gene might be expressed in blood cells but never in nerve cells. Or another gene could have an opposite expression profile. Euk gene expression is more complex, because euk cells are compartmentalized by membranes. The membranes subdivide the cell into separate organelle: nucleus = stores genetic material (dna), mitochondria & chloroplasts= recruit energy, reticulum= transports materials within the cell. These subdivisions physically separates the events of gene expression. Transcription dna->rna = in nucleus & modification (capping, polya tail, remove introns) Resulting mrnas then exported to the cytoplasm , associate w/ ribosomes (from endoplasmic reticulum) then translated into polypeptides. Physical separation of events allows regulation to occur in diff places.