BGEN 3020 Lecture Notes - Tetanospasmin, Macrophage, Pyridoxine
24 Feb 2013
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The machine has the rbc"s pass through an aperture and sizes it. And then takes an average; this is the best way for classifying an anemia. Mcv: < 80, it is microcytic (if you play odds, its fe def) Mcv (normal): 80 -100 =; have normocytic anemia; Mcv above 100 = macrocytic (b12 or folate) If you have small and large cells (dimorphic popcorn of rbc"s) it will be normocytic (like the met acidosis, and resp alk, but normal ph). Know where these things are reabsorbed fe reabsorbed in the duodenum, folate is reabsorbed in the jejunum, and b12 is reabsorbed in the terminal ileum. So if you have all these, you have small bowel dz (ie celiac dz); pt has malabsorption that affects diff areas of the bowel. Example: celiac sprue (mcc malabsorption) involves duodenum and jejunum, therefore will have def of fe and folate, and will have small cells and large cells.
