BIOL130 Lecture Notes - Scanning Electron Microscope, Antonie Van Leeuwenhoek, Great Salt Lake

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Historical light microscopy and the discovery of the cell cell theory facts, hypotheses, theories and the scientific method. Strands" of cell biology cytology, biochemistry, genetics. Basic properties shared by all cells classes of cells: prokaryotes - two kingdoms, eukaryotes- membrane-bound compartments, nucleus. Endomembrane system er, golgi, lysosomes, vesicles. Mitochondria, chloroplasts: origins of eukaryotic cells - endosymbiont theory cytoskeleton. Before microscope, it was not known that cells exsisted. Robert hooke (1635-1703) first microscope: viewed slices of cork found cellula (little rooms- actually saw cell walls) Antoni van leeuwenhoek (1632-1723: father of microbiology , worked with glass huge improvement in quality of lenses nearly 300x magnification became possible first to observe: (drew what he saw) single-celled organisms animalcules . Progress stalled for a century limited resolving power: emphasis on description rather than explanation (only drawings) Compound microscope (1830s) improved magnification and resolution: allowed visualization of objects less than 1 m.

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