BIOL 103 Lecture Notes - Frequency-Dependent Selection, Natural Selection, Gel Electrophoresis Of Proteins

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purpletortoise34

3 Mar 2013

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Genetic variation in populations is caused by: mutation (e. g. uv light hitting skin cells) Changes in dna sequences new alleles. Cannot enter population unless in gametes: sexual reproduction variable gametes. Meiosis shuffles maternal and paternal chromosomes into new combinations. Crossing over shuffles alleles into new combinations on each chromosome. Result is genetic and phenotypic variation even in absences of new mutations. Shuffling of homologous chromosomes and crossing over in meiosis leads to new gene combinations and variable gametes. The persistence of sexual reproduction in natural populations unsolved problems for evolutionary biology. In theory: male-producing, sexual populations are subject to invasion and rapid replacement by clonal females. Population of one million sexual individuals would be replaced in less than. 50 generation by a clone beginning with a single asexual female. New molecular techniques in 1960"s showed large amounts of genetic variation: new techniques such as protein electrophoresis revealed more variation than expected; excess variation = genetic load, genetic polymorphism maintained by:

Related Questions

Which statements pertaining to genetic variability are correct? Check all that apply (note that wrong answers will be deducted from right answers)!

Crossing over is defined by the exchange of chromosome pieces during metaphase one of meiosis.

If a germ cell (i.e. parent cell before meiosis) had only two pairs of homologous chromosomes (i.e. 4 chromosomes total) there are 2 possible combinations of maternal and paternal chromosomes in gametes.

Siblings produced by sexual reproduction are different because sperms are different from one another and eggs are different from one another, and the combination of an egg and sperm is basically unique.

Random fertilization means that all possible combinations of eggs and sperm are equally likely, i.e. it is pure chance which sperm fuses with which egg.

Individual chromosomes contain thousands of genes. This means that during each crossing over event, more than one gene is exchanged between paternal and maternal chromosomes.

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Need help with evolution questions:

1.) A haplotype is best defined as the ________________.

	haploid genotypes of all the gametes produced by a diploid individual

ABO blood type conferred by an individual gamete

genotype of either the paternal or maternal chromosomal complement

multilocus genotype of a chromosome or gamete

2.) Which of the following statements regarding linkage disequilibrium is true?

Exists when D is less than zero, but not when it is greater than zero.

Is reduced by sexual reproduction.

Is increased by crossing-over during meiosis.

Is increased by any random sampling error that happens to create or destroy certain chromosome genotypes but not others.

Is reduced by selection that favors certain combinations of genotypes.

3.) Selection on multilocus genotypes in random-mating populations leads to linkage disequilibrium when _______________.

it reduces mutation rates

it eliminates all haplotypes from the population

it prevents crossing-over during meiosis

some allele combinations confer greater fitness than do others

4.) When two loci are in linkage equilibrium, the allele carried on a chromosome at one locus is independent of the allele carried on the chromosome at another locus. When this is the case, _________________.

allele frequencies will not change over time

the two loci (or, more specifically, their protein products) do not interact

the frequency of each haplotype can be calculated by multiplying the frequency of its two alleles

all possible haplotypes occur at equal frequency

5.) Which of the following accurately characterize(s) Muller's ratchet model for the selective advantage of sexual reproduction?

Drift establishes linkage disequilibrium because multilocus genotypes with few mutations are eliminated by chance events.

In populations without sexual reproduction, deleterious mutations accumulate, eventually imposing such a burden that the population goes extinct.

Sex is favored selectively because it recreates the zero-mutation genotypes lost due to drift.

All of the above correctly characterize Muller's ratchet model for the evolution of sexual reproduction.

6.) The genetic signature of recent positive selection on a locus is _______________.

high frequency and low linkage disequilibrium

low frequency and low linkage disequilibrium

low frequency and high linkage disequilibrium

high frequency and high linkage disequilibrium

7.) Sexual reproduction is advantageous both in changing environments and in constant environments, compared to asexual reproduction.

True

False

8.) Sexual reproduction causes genetic recombination via crossing-over, which combines genotypes from different parents.

True

False

9.) One reason sex may be maintained in natural populations is proposed by the "Red Queen Hypothesis", which states that.....

genotypes created by sex are created by natural selection over and over

recombination creating novel genotypes that can resist infection by parasites

mutation load is reduced by novel adaptive mutations

the ability of sex to fix multiple

13. Meiosis differs from mitosis in that:
a. meiosis results in the production of two new cells, whilemitosis results in the production for four new
cells., b. meiosis is used for growth and repair, while mitosis isused for production of eggs and sperm., c.
cytokinesis can be unequal following meiosis, but is approximatelyequal following mitosis., d. meiosis
involves one cell division, while mitosis involves two celldivisions., e. meiosis results in the production of
diploid cells, while mitosis results in the production of haploidcells.
14. Bits of maternal and paternal chromosomes are exchanged betweenhomologous chromosomes during
synapsis of meiosis I. This process is called:
a. crossing over., b. random mating., c. random fertilization., d.random shuffling of parental
chromosomes.,
e. mutation.
15. The advantage of sexual reproduction over asexual reproductionis that:
a. all young are genetically identical to the parent., b. malesmust evolve a copulatory organ., c. genetic
variability in the population is increased., d. females must evolvea vagina., e. mates are not needed.
16. Many different types of information are used to constructphylogenetic trees. Which of the following types
of information is the most direct measure of evolutionaryrelatedness?
a. physiology, b. gene sequence data, c. the fossil record, d.information about the structure of ribosomes.,
e. information about the structure of enzymes
17. A species is:
a. a group of individuals that can interbreed under naturalconditions and produce fertile offspring., b.
denoted by both a genus and a species name., c. the onlybiologically defined taxon., d. a group of
organisms with a large number of traits in common., e. all of theabove.
18. The process of spermatogenesis results in:
A. 4 diploid sperm; B. 1 diploid sperm and 3 haploid polar bodies;C. 1 haploid sperm and 3 haploid
polar bodies; D. 4 haploid sperm
19. Which cell division process results in an unequal division ofthe cytoplasm?
A. Spermatogenesis; B. Testiculargenesis; C. Oogenesis; D. None ofthe above
20. Meiosis is the process by which:
A. 1 diploid cell becomes 4 haploid cells; B. 1 diploid cellbecomes 1 haploid cell and 3 haploid polar
bodies; C. 1 haploid cell becomes 4 diploid cells; D. Both A andB
21. The phase of mitosis where chromosomes line up at the equator(middle) of the cell is called:
A. Anaphase; B. Telophase; C. Interphase; D. Metaphase
22. Chromosome #6 from Mom and Chromosome #6 from Dad form achromosome pair called:
A. Sister Chromatids; B. Centromeres; C. Homologous Chromosomes; D.Spindle Apparatus

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BIOL 103 Lecture Notes - Frequency-Dependent Selection, Natural Selection, Gel Electrophoresis Of Proteins

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